Prueba de marcha de seis minutos en pacientes caninos con enfermedad valvular crónica en gran altura

E. I. Martín; M. J. Sánchez; P. P. Vargas

doi:10.30972/vet.3315890

Autores/as

E. I. Martín Universidad de La Salle, Bogotá
M. J. Sánchez Universidad de La Salle, Bogotá
P. P. Vargas Universidad de La Salle, Bogotá

DOI:

https://doi.org/10.30972/vet.3315890

Palabras clave:

perro, prueba de marcha, degeneración mixomatosa, altitud, hipoxia hipobárica

Resumen

El objetivo del presente estudio fue reconocer la relación de las variaciones en las concentraciones de lactato plasmático y de presión arterial en pacientes caninos con enfermedad cardíaca valvular crónica, sometidos a la prueba de marcha de 6 minutos en condiciones de gran altura (2650 msnm). Siete animales fueron seleccionados y se diagnosticaron a través del Servicio de Cardiología de la Clínica Veterinaria de la Universidad de la Salle, siendo clasificados como pacientes en estadio B2 según la clasificación del Colegio Americano de Medicina Interna Veterinaria (ACVIMpor su sigla en inglés). Se compararon las mediciones de la presión arterial y lactato plasmático antes y después de la prueba de 6 minutos WT. Se encontró una distancia recorrida promedio de 356.14 +/- 92.13 metros, la cual es considerablemente menor a distancias reportadas en pacientes sanos bajo las mismas condiciones medioambientales. Asimismo, se observó una reducción en la presión arterial sistólica posterior a la prueba de marcha (112.71 +/- 31.83 mmHg) comparada con los valores iniciales (132.14 +/- 26.67 mmHg) p<0.05. Esto sugiere la presentación de un fenómeno de hipotensión post ejercicio de la cual hasta ahora no se han encontrado muchos reportes en la especie canina.

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Agudelo CF, Schanilec P. 2013. Evaluation of the functional capacity in dogs with naturally acquired heart disease. Veterinarni Medicina 58: 5, 264-270.

Bergman BC, Tsvetkova T, Lowes B, Wolfel E.E. 2009. Myocardial glucose and lactate metabolism during rest and atrial pacing in humans. Journal of Physiology 587: 9, 2087-2099.

Boddy KN, Roche BM, Schwartz DS, N akayam a T, H am - lin RL. 2004. Evaluation of the six-minute walk test in dogs. American Journal of Veterinary Research 65: 3, 311¬ 313.

Borgarelli M, Buchanan JW . 2012. Historical review, epidemiology and natural history of degenerative mitral valve disease. Journal of Veterinary Cardiology 14: 1, 93-101.

Borgarelli M, Haggstrom J. 2010. Canine degenerative myxomatous mitral valve disease: Natural history, clinical presentation and therapy. Veterinary Clinics of North America, Small Animal Practice 40: 4, 651-663.

Brooks GA. 2020. Lactate as a fulcrum of metabolism. Redox Biology 35: 101454, https://doi.org/10.1016/j.redox.2020.101454.

Cerda GS, Talarico L, Todhunter R. 2016. Noninvasive assessment of neuromuscular disease in dogs: Use of the 6-minute walk test to assess submaximal exercise tolerance in dogs with centronuclear ,yopathy. Journal o f Veterinary Internal Medicine 30: 3, 808-812.

Cohen JE , Small C. 1998. Hypsographic demography: the distribution of human population by altitude. Proceedings o f the National Academy of Sciences of the USA 95: 24, 14009-14014.

Espinel CD, Ortiz RN, Vargas PP. 2019. Six-minute walk test does not affect blood pressure in healthy dogs at high altitude. Journal of Pharmacological and Toxicological Methods 99: 106595. https://doi.org/10.1016/].vascn.2019.05.067.

Glaus TM , Hauser K, Hassig M, Lipp B, Reusch CE. 2003. Non-invasive measurement of the cardiovascular effects of chronic hypoxaemia on dogs living at moderately high altitude. Veterinary Record 152: 26, 800-803.

Glaus TM , Tomsa K, Hassig M, Reusch CE. 2004. Echocardiographic changes induced by moderate to marked hypobaric hypoxia in dogs. Veterinary Radiology and Ultrasound 45: 3, 233-237.

Goutal CM, Keir I, Kenney S, Rush JE , Freem an LM. 2010. Evaluation of acute congestive heart failure in dogs and cats: 145 cases (2007-2008). Journal of Veterinary Emergency andCritical Care 20: 3, 330-337.

Grover R F et al. 1988. Pulmonary hypertension and pulmonary vascular reactivity in beagles at high altitude. Journal of Applied Physiology 65: 6, 2632-2640.

Guidry MA et al. 2003. Exercise intensity influences postexercise hypotension. Medicine & Science in Sports & Exercise 35: 1, S73.

Guyatt GH et al. 1985. The 6-minute walk: a new measure of exercise capacity in patients with chronic heart failure. Canadian Medical Association Journal 132: 8, 919-923.

Hainsw orth R, Drinkhill M J, Rivera CM. 2007. The autonomic nervous system at high altitude. Clinical Autonomic Research 17: 1, 13-19.

Keene BW et al. 2019. ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs. Journal of Veterinary Internal Medicine 33: 3.

Marcondes SM, Mansur AP, Fragata FS, Strunz CM. 2015. Short-term follow-up of exercise training program and beta-blocker treatment on quality of life in dogs with naturally acquired chronic mitral valve disease. Brazilian Journal of Medical and Biological Research 48: 10, 886¬ 894.

Orozco SC, Olivera AM, Vargas, PP. 2019. Insights on the canine mitral valve in the course of myxomatous mitral valve disease. CES Medicina Veterinaria y Zootecnia 14: 1, 40-56.

Ramirez JC et al. 2016. Bicarbonate values for healthy residents living in cities above 1500 meters of altitude. A theoretical model and systematic review. High Altitude Medicine and Biology 17: 2, 85-92.

Restan A Z, Cerqueira JA. 2019. Lactate and glucose thresholds and heart rate. American Journal of Veterinary Research 80: 3.

Rosenstein PG, Tennent BS, Hughes D. 2018. Clinical use of plasma lactate concentration. Part 1: Physiology, pathophysiology, and measurement. Journal of Veterinary Emergency and Critical Care 28: 2, 85-105.

Soares FB, Pereira GB, Rabelo RC. 2018. Assessment of plasma lactate and core-peripheral temperature gradient in association with stages of naturally occurring myxomatous mitral valve disease in dogs. Journal of Veterinary Emergency and Critical Care 28: 6, 532-540.

Swimmer RA, Rozanski EA. 2011. Evaluation of the 6-minute walk test in pet dogs. Journal o f Veterinary Internal Medicine 25: 2, 405-406.

Triposkiadis F et al. 2009. The sympathetic nervous system in heart failure. physiology, pathophysiology, and clinical implications. Journal of the American College of Cardiology, 54: 19, 1747-1762.

Valandro MA, Pascon JP, Pereira DT, Mistieri ML. 2017. Exercise training of dogs with myxomatous valve disease. Arquivo Brasileiro de Medicina Veterinaria e Zootecnia 69: 2, 325-332.

Vargas PP et al. 2016. Tolerancia al ejercicio en perros con hipertensión pulmonar tratados con sildenafil. Rev Inv Vet Perú 27: 3, 421-426.

Vargas PP et al. 2019. The six-minute walking test in dogs at high altitude. Revista de Investigaciones Veterinarias del Peru 30: 1, 49-53.

Wall L et al. 2018. Clinical use of submaximal treadmill exercise testing and assessments of cardiac biomarkers NT-proBNP and cTnl in dogs with presymptomatic mitral regurgitation. PLoS ONE 13: 6, 1-13