Efecto de la glutamina y aminoácidos de cadena ramificada en los parámetros hematológicos y bioquímicos de cachorros caninos

R. P. Mena; T. I. Llumiquinga; J. R. Quisirumbay; M. E. Villanueva

doi:10.30972/vet.3326178

Autores/as

R. P. Mena Universidad Central del Ecuador. Facultad de Medicina Veterinaria y Zootecnia Universidad Nacional Agraria La Molina. Facultad de Zootecnia. Escuela de Posgrado
T. I. Llumiquinga Universidad Central del Ecuador. Facultad de Medicina Veterinaria y Zootecnia
J. R. Quisirumbay Universidad Central del Ecuador. Facultad de Medicina Veterinaria y Zootecnia
M. E. Villanueva Universidad Nacional Agraria La Molina. Facultad de Zootecnia. Escuela de Posgrado

DOI:

https://doi.org/10.30972/vet.3326178

Palabras clave:

Cachorros, Células sanguíneas, Aminoácidos, Suplementación, Hematología

Resumen

El objetivo del estudio fue determinar la influencia de glutamina (GLN) y BCAAs (leucina, isoleucina y valina) sobre los parámetros hematológicos y bioquímicos de los cachorros. Se reclutaron 31 cachorros mestizos de 30 días, provenientes de cuatro camadas. Aleatoriamente en cada camada se estableció un grupo control (sin suplemento) y 3 tratamientos: T1 (GLN 0,5 g/kg/día/PO), T2 (BCAAs, 0.25 g/kg/día/PO) y T3 (GLN 0,5 g/kg+BCAAs 0,25 g/kg/día/PO), que se mantuvieron 90 días en ambiente controlado en igualdad de condiciones, alimentados dos veces al día individualmente, las muestras se tomaron a los 30 y 120 días de edad. Se aplicó un diseño en bloques al azar empleando a la camada como factor de bloque, se realizaron estadísticas descriptivas y pruebas de normalidad, además ANOVA para verificar variaciones entre tratamientos y Tukey para posicionar los tratamientos. A los 30 días las medias y rangos de los parámetros hematológicos y bioquímicos fueron similares. A los 120 días en los parámetros hematológicos se determinaron diferencias (p<0.05) en función del bloque, no así del tratamiento (p>0.05), sin embargo, el promedio de leucocitos (10.33 10*9/L) y el promedio de neutrófilos (7.17 10*9/L) del T2 fueron superiores al promedio del grupo control y de los otros tratamientos mostrando diferencia significativa (p<0.05) solo a un IC del 90%. Los parámetros de la bioquímica sanguínea no mostraron diferencias (p>0.05). En conclusión, se evidenció un efecto positivo en la inmunidad innata, resultando favorable la suplementación con BCAAs, sin evidencia de toxicidad.

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