Clinical efficacy of levofloxacin on the treatment of dogs affected by skin and urinary infections

Abstract

<p The efficacy and tolerance of levofloxacin for the treatment of skin and urinary tract infections were evaluated in canines. Twenty six clinical cases were included and treated orally with 10 mg/kg every 24 hours for 14 to 21 days. From the 14 cases of skin disorders, 4 corresponded to severe cases and the rest to intermediate severity. From the 12 cases of infections at urinary level, 8 corresponded to severe infections, 3 were intermediate and one was low. Treatment was successful in 99% of the cases of dermatitis. Clinical cure (score 0) was observed at day 4 for 6.25% and day 7 for 43.75% of the animals, respectively. By day 14 clinical cure was observed in 99% of patients. One patient required a 21-day treatment to reach score 0. In the population with urinary infections, all patients responded satisfactorily to treatment (clinical cure-score 0), 42% on day 4 and 83% on day 7. By day 14 clinical cure was observed in 100% of patients. No side effects were observed in any of the patients included in the study. Levofloxacin (Floxaday®, Holliday-Scott) administered orally at a dose of 10 mg/kg once a day in canines, demonstrated excellent efficacy with no adverse effects.p>