Elimination of residual concentrations of oxytetracycline and fosfomycin in colostrum and sow milk: effect on the litter
DOI:
https://doi.org/10.30972/vet.3124735Keywords:
sow, piglets, colostrum, milk, antibiotics, bacterial resistanceAbstract
The objective of this work was to study the elimination of oxytetracycline (OTC) and fosfomycin (FOS) in sow colostrum/milk and its impact on some microbiological aspects and on intestinal morpho-physiological and zootechnical parameters of the litter. Colostrum/milk samples from sows treated during the period of delivery with OTC solution and disodium FOS by the intramuscular route were analyzed. Colostrum intake with residual concentrations of antibiotics and intestinal and zootechnical parameters of suckling piglets, were evaluated. The mean residual concentrations of OTC and FOS in colostrum/milk were 0.48 and 1.55 µg/ml and the average antibiotic intake/piglet was 0.13 and 0.50 mg/kg body weight, respectively. While ingestion of colostrum with FOS residues showed less impact than OTC on the microbiological, morpho-physiological and intestinal enzymatic biochemistry of suckling piglets, any of the antibiotics affected the zootechnical parameters of the litters. Nevertheless, the low concentrations of antibiotics ingested with colostrum would be a potential risk of developing bacterial resistance, thus their prophylactic administration during the peri-partum should be reconsidered.Downloads
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