Soluciones de elevación y su potencial aplicación en resección mucosa y disección submucosa endoscópica en cerdos

M. C. Orellana; I. Ayala

doi:10.30972/vet.3124742

Authors

M. C. Orellana Comisión Nacional de Investigación Científica y Tecnológica, CONICYT, Chile
I. Ayala Departamento de Cirugía y Medicina Animal, Universidad de Murcia, España

DOI:

https://doi.org/10.30972/vet.3124742

Keywords:

pigs, endoscopy, mucosal resection, submucosal dissection, time of permanency

Abstract

Techniques such as endoscopic mucosal resection and endoscopic submucosal dissection, are minimally invasive therapeutic techniques widely spread in human medicine, but unknown in veterinary medicine. This preliminary study compared 4 gastric submucosal injection solutions: hyaluronic acid, 10% glycerol, 6% starch and 0.9% physiological saline. By injecting 5 ml of each solution into ex vivo stomachs of pigs and subsequently assessing the elevation profile of each substance and comparing groups by means of the Student’s t-test with p<0.05. The initial diameter of the mucosal elevation showed no differences between groups and was around 4 cm. The maximum height was obtained by hyaluronic acid (10.3 mm). Finally, hyaluronic acid showed a longer permanence time (68 minutes). These preliminary results are promising because they allow the first approach of veterinary doctors to these techniques.

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