Hipoglucemia como síndrome paraneoplásico en un canino de raza Fox terrier con leiomioma gástrico

C. E. Britez-Valinotti; M. Olivo; J. A. Unzain Meneses; W. V. Cardozo Areco; R. González-Vatteone

doi:10.30972/vet.3628606

Authors

C. E. Britez-Valinotti Centro Veterinario VETCIA. Universidad Nacional de Asunción. Facultad de Ciencias Veterinarias https://orcid.org/0000-0003-1685-9322
M. Olivo Universidad Nacional de Asunción. Facultad de Ciencias Veterinarias https://orcid.org/0009-0009-1732-8401
J. A. Unzain Meneses Universidad Nacional de Asunción. Facultad de Ciencias Veterinarias https://orcid.org/0009-0002-7838-3972
W. V. Cardozo Areco Laboratorio LAVET https://orcid.org/0000-0002-2671-2255
R. González-Vatteone Centro Veterinario VETCIA. Universidad Nacional de Asunción. Facultad de Ciencias Veterinarias. Dirección de Postgrado https://orcid.org/0000-0001-7165-2397

DOI:

https://doi.org/10.30972/vet.3628606

Keywords:

Canine, leiomyoma, hypoglycemia

Abstract

The aim of this study was to evaluate the clinical progression of hypoglycemia as a paraneoplastic syndrome in a dog diagnosed with gastric wall leiomyoma. A 10-yeaxr-old female Fox Terrier was presented with abdominal distension, lethargy, and weakness. Hematological evaluation showed normal complete blood count and renal profile, while the liver profile revealed elevated alkaline phosphatase and GPT. Electrolytes (Ca, P, K, Na) were within normal limits, but blood glucose was markedly decreased (35 mg dl-1). Abdominal ultrasonography revealed a mixed-echogenic mass in the epigastric region with positive Doppler signal. The patient was stabilized with 1 ml kg-1 of 50% dextrose and maintained on 5% isotonic glucose solution; however, hypoglycemia recurred upon suspension of glucose therapy. An exploratory laparotomy was performed, revealing a pedunculated, circular mass (14 x 9 x 8 cm) attached to the greater curvature of the stomach, without adhesions, and multiple hepatic nodules. The mass was excised, and the liver biopsies were obtained. Remarkably, blood glucose levels stabilized immediately after tumor removal. Histopathology confirmed the diagnosis of gastric leiomyoma. The dog remained asymptomatic, with normal glycemia and no recurrence of lethargy or weakness, for up to one-year post-surgery.

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