Efecto de dosis elevadas de florfenicol sobre algunos parámetros hematológicos en cabras adultas

M. Ruiz; F. Aguirre; R. Marengo; E. Cabaña; I. Kauffmann; J. Gallicet; L. Izquierdo; V. Notta; A. Oprandi; E. Formentini

doi:10.30972/vet.3628510

Authors

M. Ruiz Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias
F. Aguirre Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias
R. Marengo Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias
E. Cabaña Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias
I. Kauffmann Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias
J. Gallicet Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias
L. Izquierdo Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias
V. Notta Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias
A. Oprandi Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias
E. Formentini Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias https://orcid.org/0009-0003-4121-1234

DOI:

https://doi.org/10.30972/vet.3628510

Keywords:

adult goats, antibiotic, florfenicol, high doses, hematology

Abstract

The objective of this study was to evaluate the effect of high doses of florfenicol on selected
hematological parameters in adult goats. Six adult Saanen goats were treated intramuscularly with three
doses of florfenicol of 40 mg kg-1, administered at 24-hours intervals. Blood samples with anticoagulant
were collected on day 0 and on days 3, 4, 5, 6, 7, 10 and 12 after treatment initiation. The samples were
analyzed to determine erythrocytes count, hematocrit, hemoglobin, leukocytes count, neutrophils,
lymphocytes, monocytes, and platelets. High doses of florfenicol significantly affect total white blood cell
counts, particularly increasing neutrophils and monocytes. However, these findings contrast with previous
studies reporting negative effects of the same dosage on erythrocyte and leukocyte values in adult goats. The
results of this study may provide useful information for veterinarians monitoring hematological changes in
adult goats undergoing florfenicol treatment.

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