Neutralization of the hemorrhagic and edema–forming activities from venom of Bothrops alternatus offsprings from Argentina

Autores/as

  • P. A. Zeinsteger Universidad Nacional del Nordeste. Facultad de Ciencias Veterinarias
  • S. L. Maruñak Universidad Nacional del Nordeste. Facultad de Ciencias Veterinarias
  • O. Acosta de Pérez Universidad Nacional del Nordeste. Facultad de Ciencias Veterinarias

DOI:

https://doi.org/10.30972/vet.101%20y%202665

Palabras clave:

Bothrops alternatus, neutralization, hemorrhagic activity, edema–forming activity.

Resumen

Tests of neutralization of hemorrhagic and edema–forming activities from the venom of Bothrops alternatus (víbora de la cruz) one month–old offsprings were performed using a bivalent antivenom, produced by Laboratorio Central de Salud Pública in La Plata, Buenos Aires, Argentina. We determined that 172 µl of the antivenom neutralize 50 % of the hemorrhagic activity, induced by 9 µg of the venom (challenge dose). Neutralization of edema–forming activity was more effective when the antivenom was administered previous to the venom. We conclude that the antivenom neutralizes the studied toxic activities, taking into account that for its production horses are immunized using venom from adult snakes.

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Publicado

2016-10-28

Cómo citar

Zeinsteger, P. A., Maruñak, S. L., & Acosta de Pérez, O. (2016). Neutralization of the hemorrhagic and edema–forming activities from venom of Bothrops alternatus offsprings from Argentina. Revista Veterinaria, 10(1 y 2), 22–24. https://doi.org/10.30972/vet.101 y 2665

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Trabajos de Investigación

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